C. Beaton, N. Chapman, K. Clarke
1976
Citations
0
Influential Citations
18
Citations
Journal
Journal of the Chemical Society. Perkin transactions 1
Abstract
Some 2-(4-substituted phenyl)thiophens and their 3-methyl derivatives have been used to prepare substituted methylamines, ethylamines, and acetic acids with potential biological activity. Similar derivatives from 3-phenylthiophen and its 2-methyl derivative have also been prepared. Electrophilic substitution of 3-methyl-2-phenylthiophen and of 2-methyl-3-phenylthiophen takes place in the vacant α-position of the thiophen ring.