T. Johnston, A. Gallagher
Oct 1, 1961
Citations
0
Influential Citations
15
Citations
Journal
Journal of Organic Chemistry
Abstract
Several new S-substituted derivatives of 2-aminoethanethiol hydrobromide were prepared for testing as antiradiation drugs; the preferred procedure involved the aminoethylation of an appropriate sulfur-containing anion in N,N- dimethyl formamide. The oxidation of 2-aminoethanethiol hydrochloride through the action of trichloromethanesulfenyl chloride described as a simple and convenient method applicable to the preparation of large amounts of 2,2'- dithiobisethylamine (cystamine) dihydrochloride.