M. Kawada, H. Sugihara, I. Mikami
Jul 25, 1981
Citations
0
Influential Citations
10
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
Spiro [cyclopropane-1, 2'-[2H] indol]-3'(1'H)-ones with various substituents on the benzene ring and at the 1'-position were synthesized. Investigation of their biological activities revealed that significant anti-inflammatory and analgesic activities were exhibited by some compounds of this series. Their structure-activity relationships are discussed.