L. Mi
2010
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Journal
Chinese Journal of Clinical Rational Drug Use
Abstract
Objective To study the stability of compatibility of cefamandole nafate for Injection in 5% glueose,10% glueose,5% glueose and sodium chloride,0.9% sodium chloride at 25℃.Methods The combination of cefamandole nafate and infusion fluids,the content of cefamandole nafate was determined by HPLC,and examine the appearance and changes of pH.Results No significant changes of appearance and content of the mixed solution of 5% glueose and sodium chloride,0.9% sodium chloride had been observed in eight hours.Conclusion Cefamandole nafate for injection when mixed with 5% glueose and sodium chloride or 0.9% sodium chloride is basically stable,while 5% glueose and 10% glueose shoud not be used.