M. T. Baker, J. Ruzicka, J. Tinker
Apr 5, 1999
Citations
0
Influential Citations
8
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract Bromine trifluroide (BrF 3 ) reacts with succinonitrile (NCCH 2 CH 2 CN) to form 1,1,1,4,4,4-hexafluorobutane as the major product. A minor amount of bromo-1,1,1,4,4,4-hexafluorobutane (∼5% of total trapped products) was also formed. BrF 3 reacts with succinonitrile to form these hexafluorobutanes at ambient temperature or higher, in the absence of a moderating solvent, and in the absence of a catalyst. These results demonstrate that BrF 3 directly converts nitriles to trifluoromethyl moieties and is useful in the synthesis of bis-trifluoromethyl containing compounds.