H. Xiang, Yanhong Chen, Qian He
Apr 2, 2013
Citations
0
Influential Citations
29
Citations
Journal
RSC Advances
Abstract
A diversity-oriented approach to construct 2-heteroaryl-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one derivatives via copper-promoted two-step one pot reactions from chromenone derivatives has been developed. Pot, atom and step economy (PASE) were combined in these sequential reactions, and at least six bonds were formed in one pot. A number of drug-like small molecules were prepared quickly and efficiently.