P. Merino, A. Lanaspa, F. Merchán
Mar 10, 1997
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A straightforward synthesis of 2,3-diaminobutanoic acids is reported. The synthesis is based on the nucleophilic addition of methylmagnesium bromide to differentially protected nitrones derived from l -serine. The change of the protecting groups in the starting nitrone is crucial for the stereocontrol of the reaction.