A. Katrusiak
Nov 29, 1996
Citations
0
Influential Citations
5
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract The crystal structure of 3-(2,4-dimethyl-6-methoxyphenyl)-3-methylbutyric acid has been determined by X-rays: the asymmetric part of the unit cell contains four molecules, rotational conformers, hydrogen-bonded into dimers. The apparent conformational preferences of the molecular side chain cannot be directly attributed to the trimethyl lock, but is due to electrostatic interactions between substituents at the phenyl ring. Skew arrangements of hydrogen-bonded carboxylic groups are shown to stabilize the sites of the acidic protons in the crystalline state.