Qun Li, D. Chu, Kathleen Raye
Mar 5, 1996
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Journal
ChemInform
Abstract
Abstract Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from ethyl crotonate and L-alanine, respectively.