L. Smith, J. E. Lier
Jul 1, 1970
Citations
0
Influential Citations
70
Citations
Quality indicators
Journal
Atherosclerosis
Abstract
Abstract The concentration of 26-hydroxycholesterol in 36 samples of human intimal and 19 samples of human medial tissue of varying extent of atherosclerosis was estimated using thin-layer and gas chromatographic procedures. Levels of 26-hydroxycholesterol were compared with total lipid and cholesterol levels and all three entities were shown to increase in about the same manner with increasing severity of atherosclerosis both in intimal tissue samples and in medial tissue samples. These results are discussed in terms of their possible significance to the origin and progression of atherosclerosis.