Catherine M. Crawforth, I. Fairlamb, R. Taylor
Jan 12, 2004
Citations
0
Influential Citations
34
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Allylic and benzylic bromides are cross-coupled with organostannanes efficiently using the precatalyst [Pd(NCOC 2 H 4 CO)(PPh 3 ) 2 Br] 1 . Significantly, these reactions do not require the use of hexamethylphosphoramide (HMPA) as the solvent, or additional ligands, such as trifurylphosphine or triphenylarsine. Selectivity for benzyl bromide over bromobenzene is observed for precatalyst 1 , against the precatalysts, bromobis(triphenylphosphine)(benzyl)palladium(II) and bis(triphenylphosphine)palladium(II) bromide.