T. Monahan, A. F. Frost, C. Abell
Dec 20, 1976
Citations
0
Influential Citations
5
Citations
Journal
Biochemical and biophysical research communications
Abstract
Sodium periodate treated lymphocytes engage in cell to cell interaction and also yield a soluble growth factor that stimulates DNA synthesis when added to naive autologous cells. Adherent cells enhance the factor mediated activity. Sodium periodate stimulated lymphocytes, treated with mitomycin C, produced no growth factor activity. Partial characterization of the factor indicates that it is non-dialyzable, resistant to ribonuclease, and sensitive to heat, trypsin, and papain.