Marie-Aude Hiebel, Yacoub Fall, M. Scherrmann
Jul 1, 2014
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0
Influential Citations
42
Citations
Journal
European Journal of Organic Chemistry
Abstract
PEG400 is described herein as a suitable medium for the condensation of various 2-amino pyridines with α-bromo ketones. 2-Arylimidazo[1,2-a]pyridines were synthetized in a short time through microwave irradiation in moderate to excellent yields. After optimization, a convenient one-pot process enabled access to 2,3-diarylimidazo[1,2-a]pyridines by using a reduced amount of palladium catalyst without ligand for the C–H arylation step in the same environmentally-sound medium.