A. Leggio, A. Liguori, A. Napoli
Feb 1, 2000
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0
Influential Citations
17
Citations
Journal
European Journal of Organic Chemistry
Abstract
The aluminium trichloride/toluene system is investigated as a novel, unusual and straightforward reagent for the removal of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group in the solution peptide synthesis. This procedure avoids any undesired side reactions, such as the frequently observed inversion of the amino acid configuration.