V. Iaroshenko, Verena Specowius, Katharina Vlach
Aug 5, 2011
Citations
0
Influential Citations
27
Citations
Journal
Tetrahedron
Abstract
Difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles are prepared by a two step method. The regioselective cyclizations of electron-excessive aminoheterocycles, hydrazines and amidines with CF 2 Cl-substituted 1,3-dicarbonyl compounds provide the corresponding CF 2 Cl-substituted heterocycles. Subsequent radical reactions with trimethylstannane or allyltrimethylstannane gave difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles, respectively.