V. P. Reddy, A. V. Kumar, K. Rao
Feb 16, 2011
Citations
1
Influential Citations
36
Citations
Journal
Tetrahedron Letters
Abstract
Abstract trans -4-Hydroxy- l -proline is used for the first time as an effective nucleophilic coupling partner with aryl halides mediated by copper iodide with Cs 2 CO 3 as the base and DMSO as the solvent. Utilizing this protocol cross-coupling of trans -4-hydroxy- l -proline with a wide variety of substituted aryl halides to produce N -aryl pyrroles in moderate to good yields.