Omar Coughlin, Nathan de Bruyn, D. Kilgour
May 23, 2019
Citations
0
Influential Citations
2
Citations
Journal
Journal of Chemical Crystallography
Abstract
The title compound, diethyl (6-methyl-2-pyridyl)aminoethylenemalonate (1), crystallises in the monoclinic space group P21/c (No. 14). The unit cell parameters are a = 10.5657(7) Å, b = 9.1784(5) Å, c = 14.5681(7) Å, β = 101.636(6)°, Z′ = 1 and Z = 4 at 150 K. The extended structure forms approximately orthogonal columns of stacked molecules. All bond lengths and angles are unremarkable. No disorder, twinning or co-crystallised solvent is present in the structure. An intramolecular hydrogen bond exists between the enamine nitrogen and carbonyl oxygen. Hirshfeld surface analysis reveals a short contact between a carbonyl oxygen and neighbouring aryl hydrogen, as well as a carbonyl–carbonyl interaction.Graphical AbstractThe X-ray structure of diethyl (6-methyl-2-pyridyl)aminoethylenemalonate (1), an intermediate in the synthesis of ethyl nalidixate, is reported, and Hirshfeld surface analysis employed to identify intermolecular interactions within the structure.