Euisung Kim, H. Song, Choong-Souh Yun
1991
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Journal
Bulletin of The Korean Chemical Society
Abstract
The crystal structure of eprazinone dihydrochloride, 2HCl, has been determined from 2102 independent reflections collected on an automated Nonious CAD-4 diffractometer using graphite-monochromated radiation. The crystals are monoclinic, space group P/n, with unit cell dimensions a=11.381(2), b=28.318(2), c=7.840(1) , , c, F(000)=968, and Z=4. Final R value is 0.071 for independent 2102 observed reflections. The molecule assumes an extended conformation. The piperazine ring has a normal chair conformation and the four carbon atom are planar with a maximum displacement of 0.004 for C(18) atom. The two chloride ions are hydrogen bonded to the two piperazine nitrogen atoms [N(14)Cl(1); 2.986(6) N(17)…Cl(2); 3.084(8) ].