Shao, Chang-Lun, Wang
2008
Citations
1
Influential Citations
7
Citations
Journal
Chinese Journal of Structural Chemistry
Abstract
One marine natural compound, anhydrofusarubin, was isolated from the endophytic fungus No. B77 from the mangrove tree on the South China Sea coast. It was the first time that such a compound was isolated from marine fungus. The structure was identified by NMR data and mass spectrometry (MS). In addition, its structure was determined by single-crystal X-ray diffraction analysis. It crystallizes in triclinic, space group P1 with a = 8.3185(15), b = 12.397(2), c = 13.767(3) , α = 65.692(3), β = 79.266(3), γ = 75.692(3)°, C15H12O6, Mr = 288.24, V = 1248.0(4) 3, Z = 4, Dc = 1.534 g/cm3, F(000) = 600, μ = 0.120 mm-1, the final R = 0.0459 and wR = 0.1184 for 5360 observed reflections (I 2σ(I)). In the primary bioassay, the title compound shows strong inhibitory activity against Gram-positive bacteria Staphyococcus aureus (ATCC27154) with the MIC value of 12.5 μg/mL.