C. Clews, W. Cochran
Mar 1, 1948
Citations
1
Influential Citations
36
Citations
Journal
Acta Crystallographica
Abstract
The structures of two isomorphous pyrimidines 2-amino-4-methyl-6-chloropyrimidine and 2-amino-4,6-dichloropyrimidine have been studied by X-ray methods. The molecules are based on planar six-membered rings with the C—C and C—N bonds in the ring having approximately 50% double-bond character. It is found that for the compound containing the methyl group, the methyl groups and the chlorine atoms are distributed at random throughout the structure in two chemically, but not crystallographically, equivalent positions in the molecules. The structure is held together by the van der Waals forces between the chlorine atoms of adjacent molecules and by a system of hydrogen bonds.