S. Kalia, G. Kaushal, Manoj Kumar
Sep 1, 2008
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Influential Citations
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Journal
Indian journal of chemistry. Sect. A: Inorganic, physical, theoretical & analytical
Abstract
New 4-methylpiperazine-l-carbodithioate (4-MPipzcdt) complexes of the general formula [M(4-MPipzcdtX)2](Y) 2 (M = Zn(ll), X = H and Y = ClO 4 , Cl; M = Cd(II), Hg(II), X = H and Y = Cl; M = Zn(II), Cd(II), Hg(II) when X and Y = nil) and mixed-ligand complexes, viz. [M(4-MPipzcdtX)a(L) b ]Y (L = 1,10-phenanthroline (phen) and 2,2'-bipyridyl (bipy); M = Zn(II), Cd(II), Hg(II), X = H when Y = Cl 2 , a = 2, b = 1; M = Zn(II), X = nil where Y = Cl when a = 1, b = 2 and Y = nil when a = 2, b = 1) have been prepared and characterized by elemental analyses, conductance measurements, proton nuclear magnetic resonance, infrared and electronic absorption spectral, and room-temperature magnetic susceptibility measurements. Two of these complexes, viz. Zn(4-MPipzcdt) 2 and [Hg(4-MPipzcdtH)2](Cl)2 have been screened for their in vitro antimicrobial activity against the pathogenic fungus Candida albicans and pathogenic gram-negative Escherichia coli, Pseudomonas aeruginosa and gram-positive Staphylococcus aureus, Enterococcus faecalis using the agar dilution method. Two complexes, viz. M(4-MPipzcdt) 2 (M = Zn(II), Cd(ll)) have also been screened for their antileukemic activity.