Govindkumar R. Varde, G. Acharya
Dec 5, 2017
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Journal
International journal of scientific research in science, engineering and technology
Abstract
The novel ligand 4-(ethyl((5-(naphtho[2,1-b]furan-2-yl)-2-thioxo-1,3,4-oxadiazol-3(2H)-yl)methyl)amino)-2hydroxybenzoic acid (EENFODMSA) was synthesized by Mannich reaction between 5-(naphtho[2,1-b]furan-2-yl)1,3,4-oxadiazole-2(3H)-thione (NFOD) and p-(ethylamino) salicylic acid (ESA). The synthesized ligand was characterized by elemental and spectral studies. Furthermore, transition metal chelates of EENFODMSA were evaluated for their chelating properties using by metal-ligand (M:L) ratio, IR, reflectance spectral study and magnetic properties. Also the all transition metal chelates and their parent ligand were examined for their antifungal activity against different fungal strains.