T. Kametani, K. Kigasawa, M. Hiiragi
May 1, 1977
Citations
0
Influential Citations
8
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
The thermal cyclization of the arninomethylenemalonates (8) gave the 4-hydroxynicotinates (9), ethylation of which yieldedN-ethylated (11) and O-ethylated products (12). Hydrolysis of 9, 11, and 12 led to the desired nicotinic acids (10, 4, and 13), respectively.