Wei Zaho, Y. Tezuka, T. Kikuchi
Nov 25, 1989
Citations
0
Influential Citations
19
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
The constituents of the roots and rhizoma of Veratrum maackii REG. (Liliaceae), wich are used as a Chinese crude drug "Li-lu, " were examined and a new steroidal alkaloid named maackinine was isolated along with five known alkaloids, germanitrine, verazine, angeloylzygadenine, zygadenine, and verazinin. The structure of maackinine was determined by the use of two-dimensional nuclear magnetic resonance (2-D NMR) techniques (fl-decoupled 1H-1H chemical shift correlation spectroscoy (COSY), 1H-1H COSY, 1H-13C COSY, and long-range 1H-13C COSY spectra). Assignments of 1H- and 13C-NMR signals of these steroidal alkaloids were also performed.