K. Fukui, M. Nakayama, T. Horie
Aug 1, 1969
Citations
0
Influential Citations
8
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The partial benzylation of 3-methoxy-2,4,6-trihydroxyacetophenone gave a mixture of 2,4-dibenzyloxy-6-hydroxy- and 4,6-dibenzyloxy-2-hydroxy-3-methoxyacetophenone. The latter was esterified with 4-benzyloxy-3-methoxybenzoyl chloride, and the resulting ester was converted into 8,3′-dimethoxy-5,7,4′-tribenzyloxyflavone via the corresponding diketone. The catalytic debenzylation of the flavone gave 8,3′-dimethoxy-5,7,4′-trihydroxyflavone. Its diethyl ether was also prepared from 3,6-dimethoxy-4-ethoxy-2-hydroxyacetophenone by an unambiguous method.