N. Hirayama, K. Shirahata, Y. Ohashi
Nov 1, 1980
Citations
0
Influential Citations
3
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Fortamine dihydrochloride, C8H18N2O4·2HCl, is obtained by the hydrolysis of fortimicin B with hydrochloric acid. The space group is C2 with a=16.109(2), b=10.047(1), c=8.603(1) A, β=108.69(1)°, and Z=4. The structure was solved by the heavy atom method, and least-squares refinement using 1564 reflexions led to the final R value of 0.030. The ring conformation of fortamine dihydrochloride is an inversed chair form of fortamine. The chair form is significantly compressed to relax the non-bonded interactions between axial substituents.