L. Gjessing
1963
Citations
0
Influential Citations
31
Citations
Quality indicators
Journal
Scandinavian journal of clinical and laboratory investigation
Abstract
1) Ten 3-niethoxy-phenyl-metabolites of dihydroxy-phenylalanine, dopamine, norepinephrine, epinephrine, and N-methyl-epinephrine were investigated in urine from 10 patients with functional neural tumors. The acids, alcohols and amines were determined with paper chromatography and the amino-acid 3-methoxy-4-hydroxy-phenylalanine with high voltage electrophoresis combined with chromatography. All' these ten above-mentioned metabolites are stable and easy to determine compared with the unstable catechol metabolites themselves.2) The acids, 3-methoxy-4-hydroxy-man-delic acid and/or 3-methoxy-4-hydroxy-phe-nylacetic acid, are overexcreted by all these 9 cases of functional neural tumors. Very high values of these acids point to longlasting generalized metastases.3) The alcohols, 3-methoxy-4-hydroxy-phenyl-glycol and 3-methoxy-4-hydroxy-phenyl-ethanol, vary mainly with the acids and with age. The younger children have relatively higher values of these alcohols in proportion to the acids than the older children....