Y. Murakami, Masanobu Tani, Michio Suzuki
Nov 25, 1985
Citations
0
Influential Citations
16
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
Ethyl indole-2-carboxylate (1a) and its derivatives were reacted with various carboxylic acids by using trifluoroacetic anhydride and phosphoric acid (or polyphosphoric acid) to yield effectively the corresponding ethyl 3-acylindole-2-carboxylates (3). However, strongly acidic carboxylic acids and nitrogen-containing carboxylic acids were poor acylating agents. Ethyl 3-acylindole-2-carboxylate (3) could easily be converted to 3-acylindole (5)