T. Masamune, H. Matsue, H. Murase
Apr 17, 1979
Citations
0
Influential Citations
24
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The synthesis of cis-2-ethyl-8-formyl-3,4,7,8-dihydro-2H-oxocin-3-one and its derivatives, key intermediates for synthesis of laurencin, from methyl 2-ethyl-2,5-dihydro-2-furoates is described. The structure and configuration of these compounds and the synthetic intermediates are defined clearly on the basis of the chemical and spectral evidence.