Shigekazu Sasaki, Y. Hamada, T. Shioiri*
Apr 28, 1997
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A core building block 3 for (2 S,3 R,4 S,5 S,6 S,11 E)-3-amino-6-methyl-12-(4-methoxyphenyl)-2,4,5-trihydroxydodec- 11-enoic acid (2, AMMTD) has been efficiently synthesized using the Sharpless asymmetric dihydroxylation and the Dondoni's furan addition to a nitrone derivative as key steps. The 2-furyl group has been used as the carboxyl synthon. © 1997 Elsevier Science Ltd.