K. Hirai, K. Ogawa
1975
Citations
0
Influential Citations
20
Citations
Quality indicators
Journal
Acta Histochemica Et Cytochemica
Abstract
The morphogenesis of peroxisomes was investigated ultrastructurally in hepatocytes of normal mice and mice given simfibrate (hypolipidemic agent) in a daily dose of 1, 000mg/kg for 1 to 14 days.Continuity between the rough endoplasmic reticulum and peroxisomes of different sizes was most frequently observed. A characteristic loop- or hook-shaped smooth endoplasmic reticulum was often visualized as a continuity with peroxisomes or with the rough endoplasmic reticulum. These observations lead to the suggestion that the loop- or hook-shaped smooth endoplasmic reticulum may play an important role in the initial stage of formation of mouse peroxisomes.