Y. Ikutani
Jul 1, 1968
Citations
0
Influential Citations
13
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The N,N-dimethyl derivatives of neutral amino acids, such as glycine. L-alanine, DL-alanine, L-valine, DL-valine, L-leucine, L-phenylalanine, and L-tyrosine, were prepared by the catalytic reductive condensation of the corresponding amino acids with formaldehyde. The N-oxides were satisfactorily synthesized by the oxidation of the N,N-dimethyl derivatives with an aqueous mixture of hydrogen peroxide and acetic acid. The reaction conditions, the analytical data, and some properties of the products are presented.