C. Yuan*, Shoujun Chen, Guifeng Wang
1991
Citations
0
Influential Citations
29
Citations
Journal
Synthesis
Abstract
Acetyl chloride is used successfully in the synthesis of 1-aminoalkyl- and amino(aryl)methylphosphonic acid derivatives by a three-component condensation reaction involving diethyl phosphoramidate, aldehydes and diphenyl phosphite. Furthermore, in the reaction of benzyl carbamate, aldehydes and phosphorus(III) chloride, acetyl chloride facilates the formation of alkyl hydrogen 1-(benzyloxycarbonylamino)alkylphosphonates or aryl(benzyloxycarbonylamono) methylphosphonates, key intermediates in the synthesis of phosphonopeptide with a P-N bond