K. Haga, M. Kainosho, M. Yoshikawa
Feb 1, 1971
Citations
0
Influential Citations
7
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Two isomers of inosine-5′-thiophosphates, inosine-5′-phosphorothionate and 5′-deoxy-5′-thioinosine-5′-phosphorothioate, were synthesized by the direct phosphorylation of inosine with phosphorus thiochloride, and by the treatment of 5′-deoxy-5′-iodoinosine with trisodium phosphorothioate, respectively. The structure of the thiophosphate residues was identified by means of 31P NMR. The flavoring activities of these thiophosphates were measured as the synergistic strength with monosodium glutamate; it was found that the strength of each compound was lower than that of inosine-5′-phosphate.