M. Rozwadowska, D. Matecka
Mar 12, 1991
Citations
0
Influential Citations
4
Citations
Journal
European Journal of Organic Chemistry
Abstract
The two new phthalideisoquinoline hemiacetals rac-egenine (3) and rac-corytensine (4) are prepared by stereoselective DIBAL reduction of rac-bicuculline (1) and rac-adlumidine (2), respectively. The identity of egenine (3) with decumbensine as well as of corytensine (4) with epi-α-decumbensine and humosine A is postulated. The configuration around the anomeric center in natural (+)-egenine (3), (+)-corytensine (4) and (−)-narcotine hemiacetal (7) is deduced as (7′S), (7′R) and (7′R), respectively.