J. Hubble
May 1, 2000
Citations
4
Influential Citations
48
Citations
Journal
European Journal of Neurology
Abstract
This paper reviews the preclinical study of the novel dopamine agonist pramipexole and its use in early Parkinson’s disease (PD). Emphasis will be given to those properties distinguishing this drug from other dopamine agonists, the relevance of the preclinical data to clinical trial results in early PD, and the putative neuroprotective properties of the compound.