N. Sato, H. Kadota
Dec 1, 1992
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0
Influential Citations
11
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Homolytic acylation of 2-amino-3-cyanopyrazine (1) with α-keto acids led to the formation of 6-acylated compounds in 74-85% yields. Methyl 3-aminopyrazinecarboxylate (2) and 3-aminopyrazinecarboxamide (3) were also acylated under the same conditions although in lower yields. The observed reactivity of acylation is explained by comparison with the homolytic reactions of related pyrazines.