T. Sakamoto*, Y. Kondo, H. Yamanaka
Jul 25, 1982
Citations
0
Influential Citations
16
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
2, 4-Dimethyl-6-phenyl-furo-and-thieno-[2, 3-d]-pyrimidine were synthesized by cross-coup ing of 2, 6-dimethyl-5-iodopyrimidines with phenylacetylene in the presence of palladium catalyst, followed by cyclization of the resulting phenylethynylpyrimidines. 2, 4-Dimethyl-6-phenyl [2, 3-d] pyrimidine was also synthesized by the thermal decomposition of 4-azido-2, 6-dimethyl-5-styrylpyrimidine, which was obtained from the 4-chloro derivative.