K. Majumdar, U. Das, N. Jana
May 13, 1998
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0
Influential Citations
38
Citations
Journal
Journal of Organic Chemistry
Abstract
A number of pyrrolo[3,2-d]pyrimidine derivatives (5a−f) were synthesized in 90−95% yields from the corresponding 5-[N-[4-(aryloxy)but-2-ynyl]-N-ethylamino]-1,3-dimethyluracils 4a−f by simple treatment with 1 equiv of m-chloroperoxybenzoic acid in dichloromethane at 0−5 °C for 12−15 h. The resulting benzoates (5a−f) were easily converted to methoxy derivatives 11a−f in 92−94% yields when refluxed in methanol for 20−22 h.