T. Abiko, M. Kumikawa, S. Dazai
May 30, 1978
Citations
0
Influential Citations
3
Citations
Journal
Biochemical and biophysical research communications
Abstract
Abstract The discovery of dipeptide, H-Asp(Gly)-OH, having an inhibition activity of PHA-induced lymphocyte transformation is reported. The seven analogs of H-Asp(Gly)-OH are described in which H-β-aspartyl, H-D-β-aspartyl, and Z-β-aspartyl respectively. The H-Gly-OH residue of H-Asp(Gly)-OH is also substituted for H-Sar-OH, H-β-Ala-OH, and H-Gly-OMe respectively. The biological activity of the seven analogs is compared with that of H-Asp(Gly)-OH on a PHA-induced lymphocyte transformation.