D. Buckle, D. J. Outred, C. J. Rockell
Oct 1, 1981
Citations
0
Influential Citations
7
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Ethyl 1-benzyl-5-chloro-v-triazole-4-carboxylate (3) undergoes facile nucleophilic displacement of the halogen atom with phenoxide ion to yield aryloxytriazolecarboxylates 4 which debenzylate under hydrogenolytic conditions to N-H triazoles 7. Saponification and cyclization with either polyphosphoric acid or phosphoric oxide in methanesulphonic acid leads to the novel 9-oxo-1H,9H-benzopyrano[2,3-d]-v-triazole system 9, members of which have potential as antiasthmatic agents.