Xiao You-jun
2008
Citations
0
Influential Citations
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Citations
Journal
Journal of Jiangxi University of Science and Technology
Abstract
At present 2,4-dichlorofluorobenzene is used as an important organic intermediate for synthesizing ciprofloxacin.The process adopted by the domestic factories is extremely unsafe,The paper adopts a synthesizing route taking easily-controlled o-Dichlorobenzene with temperate condition and safe process as raw material.The craft of nitrating reaction,fluorination and chlorination are studied,which helps to enhance the reaction total yield greatly.The results will benefit domestic correlative factories.The optimum technology can ensure the safety of the processing taking 2,4-Dinitrochlorobenzene as raw material.