V. Vladimirov, I. I. Krasil'nikov, A. P. Volgarev
Jul 1, 1991
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Voprosy virusologii
Abstract
Tri-substituted benzamide derivatives are described as a new class of antiviral drugs. Three compounds (3, N-acetylaminobenzamide, 3, N-butyrylaminobenzamide, and 3-methoxybenzamide) protected mice inoculated with influenza type A virus. 3, N-acetylaminobenzamide was found to be most active. It is suggested that the antiviral effect may be due to the specific inhibitory action of these compounds on NAD(+)-dependent ADP-ribosylation.