S. Cunha, Maı́sa B Costa, H. Napolitano
Feb 25, 2001
Citations
0
Influential Citations
42
Citations
Journal
Tetrahedron
Abstract
Abstract In this work, it is demonstrated that the benzoyl group is an activating group for thioureas in the HgCl2-guanylation reaction. Thus N-benzoyl-thioureas containing electronically neutral and even electron-withdrawing or electron-releasing substituents are converted into guanidines with reasonable yields. In addition, NMR and X-ray structural analyses were performed to understand the intra- and intermolecular features of the synthesized guanidines.