L. Peng
2011
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Journal
China Pharmacy
Abstract
OBJECTIVE:To study the compatibility of Carbazochrome sodium sulfonate injection and Gatifloxacin for injection in 0.9% sodium chloride injection. METHODS:Carbazochrome sodium sulfonate injection was combined with gatifloxacin for injection in 0.9% sodium chloride injection. The contents of carbazochrome sodium sulfonate and gatifloxacin in mixture were determined by RP-HPLC-DAD at 25 ℃ or 37 ℃ within 12 h and external appearance and pH were observed. RESULTS:There was no significant change in appearance,pH and the content of carbazochrome sodium sulfonate and gatifloxacin under two temperature conditions within 12 h. CONCLUSION:Carbazochrome sodium sulfonate injection combined with gatifloxacin for injection in 0.9% sodium chloride injection can be used within 12 h at 25 ℃ and 37 ℃.