R. Hiller
Mar 1, 1970
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
American Journal of Surgery
Abstract
Abstract Fluorescent and other studies in human breast epithelium indicate an affinity of the established pharmacalogically and therapeutically tested compound, quinacrine dihydrochloride, for nucleoli, nuclear membranes, and intranuclear granules. The elastica of the arterioles and small arteries was also found to bind the drug. Collagen and fibrocytes reacted in various ways. The pH, concentration, and time appear to be determining factors. Further clinical studies appear justified in selected cases.