J. Gibka, T. Majda, Anna Tichek
May 1, 2008
Citations
0
Influential Citations
7
Citations
Quality indicators
Journal
Journal of Essential Oil Research
Abstract
Abstract The in vivo effects of 3-undecanone and 3-undecanol on the cellular and humoral immunity were studied in inbred Balb/c mice. Mice were subjected to the inhalation of both compounds for three days. An increase of antibody production and increase of the lysozyme level in sera of mice which inhaled 10% 3-undecanol were observed. Mice that inhaled 3-undecanol presented a higher activation of respiratory burst (RBA test) and phagocytic activity of blood granulocytes (PKA test) than the corresponding controls. In the group that inhaled 3-undecanol the proliferative response of lymphocytes isolated from blood and the spleen to mitogens ConA and LPS was significantly higher than in the controls. The mice that inhaled 3-undecanone no immunostimulatory effects were observed