G. Wang, F. Jing, S. Su
Jul 1, 1999
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Influential Citations
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Quality indicators
Journal
Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns
Abstract
OBJECTIVE To study the characteristics of metacresol burn. METHODS Metacresol of 99.6% was used. The animals were randomly separated into control group, excision group, topical SD-Ag group, saturated sodium sulfate wet compress group, and warm running water flushing group. RESULTS It was proved that metacresol could not only cause deep burns to skin but also penetrate skin and to produce impairment of functions of the main internal organs of the body, as shown by abnormalities in blood BUN, GPT, GOT, GGT, and AKP. Pathological changes were also found in the liver, heart, brain, kidney, and skin with light and electron microscopy. CONCLUSION Through comparison of the four different treatment methods for metacresol burns, it is concluded that excision of the wound followed by skin grafting should be done as early as possible to minimize absorption of the chemical. Topical application of SD-Ag or sodium sulfate wet compress, and flushing with running water can alleviate direct injury to skin. Drugs to protect the heart, liver, and kidney should be used for a longer period than usual.