I. Čikotienė, Erika Pudziuvelyte, A. Brukštus
Aug 20, 2007
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron
Abstract
Abstract Reactions of 4-amino-5-nitro-6-phenylethynylpyrimidines with amines and thiols have been investigated. Pyridine catalyzes rearrangement of the title compounds into 6-phenyl-7-oxo-7 H -pyrrolo[3,2- d ]pyrimidine-5-oxides. Primary and secondary amines and thiols take part in a regio- and stereoselective addition reaction to the triple bond of 5-nitro-6-phenylethynylpyrimidines to form the corresponding syn -addition (in the case of secondary amines) or anti -addition (in the case of primary amines or thiols) products.