Fang Bao-xia, Wu SongChao, Shi Xiaoya
2010
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Journal
Practical Pharmacy and Clinical Remedies
Abstract
Objective To study the stability of carbazochrome sodium sulfonate in invert sugar and electrolytes injection. Methods HPLC method was adopted in which the Hypersil ODS-C18 was taken as the chromatographic column,phosphate buffer-acetonitrile( 85∶ 15) as the mobile phase. The contents were determined at room temperature within 8 h,and the appearance of the solution was observed,the pH value was determined. Results Compatibility of pH value and the appearance of change had no significant change,carbazochrome sodium sulfonate content decreased significantly. Conclusion The mixture of carbazochrome sodium sulfonate for injection in invert sugar and electrolytes injection is instability.